.webp)
Aesthetic medicine is evolving beyond treating volume loss, contour, or skin quality as separate concerns. Increasingly, the focus is on more comprehensive treatment strategies that combine immediate structural correction with approaches designed to support longer-term tissue quality.
Hybrid biostimulation is part of this shift.
But what does hybrid biostimulation mean in clinical practice? How does the approach differ between the face and body? And where do combination protocols fit into modern aesthetic treatment planning?
These questions take centre stage in the next episode of The Aesthetic EDGE, presented by BioScience in collaboration with IMCAS Academy.

Bringing together four expert speakers and their perspectives across facial and body aesthetics, this BioScience x IMCAS Academy webinar will explore the science of skin quality, clinical evidence for hybrid biostimulation and advanced combination protocols for body contouring.
Traditional injectable treatments have often been discussed according to a primary function: restoring volume, improving contours, enhancing hydration or stimulating tissue.
Modern aesthetic medicine is becoming less compartmentalised.
Hybrid biostimulation reflects an approach in which structural correction and biostimulatory activity are considered together, with the aim of addressing both visible aesthetic concerns and aspects of tissue quality within a broader treatment strategy.
This is particularly relevant as patient expectations continue to move towards results that look natural, work with existing anatomy, and consider how the skin and underlying tissues change over time.
For aesthetic practitioners, this means looking beyond a single endpoint. Volume, projection, skin quality, tissue support, and collagen stimulation may all form part of the clinical decision-making process depending on the patient, indication, and treatment area.
Episode 3 of The Aesthetic EDGE takes a closer look at how these principles translate into practice.
Skin quality has become an increasingly important consideration in modern facial aesthetics.
Rather than focusing exclusively on lines or volume loss, a more comprehensive assessment can consider characteristics such as skin texture, hydration, firmness, and overall tissue quality alongside facial structure and proportions.
This is where biostimulatory approaches have become particularly relevant.
During The Science of Skin Quality & Hybrid Biostimulation, Dr. Gabriela Casabona will examine the science behind skin quality and the role hybrid approaches can play within contemporary aesthetic treatment strategies.
The session provides a foundation for understanding why the conversation around injectables is expanding beyond correction alone, and how different mechanisms and treatment objectives can be considered together when developing an individualised aesthetic plan.
Moving from scientific principles to clinical evidence, the webinar will then turn to Genefill DX.
Genefill DX combines hyaluronic acid and dextranomer in a hybrid formulation developed for facial aesthetic applications. This combination brings together the volumising properties associated with hyaluronic acid with a biostimulatory component, creating a different approach to facial correction and tissue quality.
But understanding a hybrid injectable requires more than looking at its individual components.
Clinical evidence is essential for understanding how a product performs, how it should be integrated into treatment planning, and what practitioners should consider when selecting patients and indications.
In Genefill DX: Clinical Evidence for Hybrid Biostimulation, Dr. Luis Mastronardi will explore the available clinical perspective behind this hybrid approach, connecting the science of biostimulation with its practical relevance in facial aesthetics.
For practitioners interested in hybrid dermal fillers, facial biostimulation, regenerative aesthetics and evidence-based injectable treatments, this session will provide a closer look at how these concepts can translate from theory into clinical practice.
The principles behind combination treatments are not limited to the face.
Body contouring presents its own anatomical and mechanical considerations. Treatment areas can be larger, tissue characteristics differ, and aesthetic objectives may include projection, contour, proportion, and the correction of specific depressions or irregularities.
This makes product selection and treatment planning particularly important.
In Advanced Body Contouring: Combination Protocols with HYAcorp, Dr. Patricia Oliveira will explore treatment strategies that combine HYAcorp hyaluronic acid body fillers with biostimulatory approaches.
Rather than viewing each treatment modality in isolation, the session will focus on how combination protocols can be considered within a broader body-contouring plan.
For those working with non-surgical body contouring, HA body fillers and collagen biostimulation, the session offers an opportunity to explore how different approaches may complement one another while addressing the specific requirements of body aesthetics.
Episode 3 has been structured to move from scientific foundations to clinical application across both facial and body aesthetics.

Welcome Introduction
Dr. Jani van Loghem will open the session and introduce the central theme of hybrid biostimulation, setting the context for the discussions that follow.

The Science of Skin Quality & Hybrid Biostimulation
The first scientific session examines skin quality, biostimulation, and the principles supporting a more integrated approach to aesthetic treatment.

Genefill DX: Clinical Evidence for Hybrid Biostimulation
The discussion then moves into clinical evidence, with a focused look at Genefill DX and the role of hybrid biostimulation in facial aesthetics.

Advanced Body Contouring: Combination Protocols with HYAcorp
The final clinical presentation expands the conversation from face to body, exploring combination treatment strategies involving HYAcorp in advanced body contouring.
The webinar concludes with an extended Q&A and key clinical takeaways, giving attendees the opportunity to consolidate the topics covered throughout the session.
There is no universal aesthetic treatment protocol.
Facial anatomy, tissue quality, ageing patterns, body morphology, treatment objectives and individual patient characteristics can all influence clinical decision-making.
This is why combination strategies have become an important area of aesthetic medicine education.
Rather than simply adding treatments together, an effective combination protocol requires practitioners to understand what each treatment is intended to achieve, how different approaches interact, and why a particular sequence or technique is appropriate for the individual patient.
The goal is not necessarily to do more. It is to make treatment planning more considered.
By exploring hybrid biostimulation across both the face and body, Episode 3 connects several areas currently shaping aesthetic practice: skin quality, hyaluronic acid fillers, collagen stimulation, regenerative aesthetics, facial contouring and non-surgical body contouring.
The Aesthetic EDGE — Education, Development, Growth and Expertise — is BioScience's educational webinar series developed in collaboration with IMCAS Academy.
Each episode brings focused aesthetic medicine topics together with expert-led discussion, clinical perspectives, and practical considerations for healthcare professionals.
Previous episodes have explored advanced treatment techniques and evolving approaches within aesthetic medicine. Episode 3 continues the series by examining one of the field's most relevant developments: the growing intersection between structural correction, biostimulation and combination treatment protocols.
The aim is to move beyond isolated product discussions and create a wider educational conversation around how modern aesthetic treatments can be planned, evaluated and applied in clinical practice.
Episode 3 is designed for healthcare professionals with an interest in aesthetic medicine, including practitioners working with:
Whether your practice is primarily focused on facial aesthetics, body treatments, or both, the webinar provides a broader look at how biostimulation and combination protocols are influencing contemporary treatment strategies.
Hybrid biostimulation refers to an aesthetic approach that brings together more than one treatment objective, such as structural or volumetric correction alongside biostimulatory activity. The specific mechanism and clinical effect depend on the products and techniques being used.
The webinar will cover the science of skin quality and hybrid biostimulation, clinical evidence relating to Genefill DX and advanced combination protocols involving HYAcorp for non-surgical body contouring.
Both. Episode 3 has been designed to connect facial and body aesthetics within one discussion, moving from skin quality and facial hybrid biostimulation to combination strategies for advanced body contouring.
Hybrid Biostimulation: From Clinical Evidence to Combination Protocols for Face & Body takes place on Monday, 21 September 2026 at 15:00 UTC.
The future of aesthetic medicine is not simply about choosing between correction and stimulation.
It is about understanding how different treatment approaches can work within a thoughtful, evidence-led strategy.
Join BioScience and IMCAS Academy for Episode 3 of The Aesthetic EDGE as leading experts explore the science, clinical evidence, and combination protocols shaping the next generation of facial and body aesthetic treatments.
Subscribe to be the first to know our latest news and projects.
